Oral pemphigoid pemphigus
Pemphigus is a group of diseases which affect the skin and mucous membranes. These diseases are autoimmune, which means that they arise in response to materials and tissues in the body. The disease causes blisters on the affected skin and mucous membrane.
There are three types of Pemphigus:
- Pemphigus Vulgaris, this is the most common type. When the antibodies attack the Desmoglein 3, this disease begins. Due to this, sores are formed in the mouth. These sores make eating and speaking very painful. It is a rare disease which causes painful blistering on the skin and the mucous membranes. It mainly attacks the healthy tissues.It is one of the most common types of autoimmune disease.
- Pemphigus foliaceus, this disease originates when the antibodies demolish the Desmoglein 1. Since Desmoglein 1 exists in the top layer of the skin, this type of Pemphigus is the least severe among the three. It is generally an autoimmune skin disorder characterized by the loss of the intercellular adhesion of the keratinocytes in the upper parts of the epidermis.
- Paraneoplastic Pemphigus, this is the most severe type of the disease and very rare. Basically, it is a complication of cancer and the condition may lead to the occurrence of tumors. With this disease, sores are formed in the mouth, lips, and esophagus. It may also infect the lungs. It is also an autoimmune disorder arising from an underlying tumor. It is observed that antigens associated with the tumor lead to the blistering of the skin and mucous membranes.
Pemphigus disease can be life-threatening if treatment is not started immediately. Thus as per the dental hygiene tips for better oral health, steroids and medications are prescribed by physicians and these can have severe side effects, however, until the treatment is completed and the disease is cured, it is necessary to continue the medication.